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Membranes and Microforces

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Mcube team web site

The team “M3: Membranes and microforces” came into being in January 2005. Its members share a common interest in complex interfaces in general and self-assembled phospholipid systems in particular. They study the behaviour of these systems from the physical, experimental and theoretical points of view and dispose of a common experimental expertise, encompassing notably micromanipulation techniques and the measurement of microforces.

One of the originalities of our research is that it associates a strong experimental component with important efforts in the field of modelling. We develop and use a large number of experimental techniques specifically adapted for our systems, some of these methods being unique. We probe the structure and dynamics of interfaces on a level ranging from the nanometre to the millimetre scale, combining techniques of light or X-ray diffraction and optical microscopy. Finally, we analyze the response of these systems to applied forces, using methods allowing the measurement of forces in confined situations and micromanipulation.

The work of the group is divided into three areas of research:

  • Lipid bilayers: giant vesicles and deposited membranes
  • Surfaces: direct measurement of surface forces and kinetics of adhesion
  • Systems out of equilibrium morphology, mechanisms and dynamics

The principal collaborations of the group M3 include: LIONS (CEA Saclay, France), Sejong University (Seoul, South Korea), Constance University (Germany), Sao-Paulo University (Brazil) and the University of California UC Davis (USA).

Detailed information on the team, its members, their research activities and their publications may be found on the M3 web site, at the address http://www.ics-cnrs.unistra.fr/Mcube/.

Key words: surface force apparatus (SFA), fluorescence recovery after photobleaching (FRAP), large instruments (X-ray and neutron diffraction), fluorescence and confocal microscopy, reflection interference contrast microscopy (RICM), micropipette manipulation, electroformation of vesicles, supported phospholipid bilayers, controlled adhesion, polymer-membrane interactions.

Members of the team:

Lien vers site d’equipe

Anciens membres

  • Salamone Salvatore
  • Walter Vivien
  • Kluzek Monika
  • Morandi Mattia
  • Hemmerle Arnaud
  • Kuhl Tonya
  • Marcopoulos Constantin
  • Malaquin Linda
  • Amoussou Balbine
  • Barber Suzanne
  • Sun Yuting
  • Weber Georges
  • Gomez Dantas Wellington
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